Nyx
Nyx was one of the disciples of Chaos. Like him, she relished destruction on a multiversal scale and detested Jenny Everywhere.
Nyx was one of several agents of Chaos with shapeshifting abilities. She chose her bodies with great precision, making them startlingly durable but also implementing failsafes that turned her body into a nuclear bomb in the event of her being killed. The Jenny Everywhere who travelled aboard the Wilson, and the rest of the crew, tried to defeat her numerous times, but had not yet managed it by the time Michael was lost.
Nyx once ended up brawling with Jenny without her having realised quite which agent of Chaos she was battling. She shifted the two of them to the middle of the sky in a random inhabited universe; Jenny summoned a parachute for herself while Nyx let herself fall, counting on the durability of her body. However, the weight of her impact buried her in a deep crater, halting her battle with Jenny as she scrambled to find a form that would allow her to climb out of the pit.
When she finally climbed out, Jenny had been joined by Raleigh, another Wilson crewmember, who'd told her that it was Nyx she was fighting. However, the random raygun she summoned from another dimension proved unable to lay Nyx down or even meaningfully harm her, giving Nyx an opening to stab Raleigh with one of the large scythe-like claws of the form she had chosen. Jenny teleported Raleigh to safety then used a sword to hack Nyx apart, with speed that startled even her.
However, Nyx, collapsing to the ground, warned Jenny that her body was even now preparing a nuclear charge powerful enough to destroy the planet. In one last act of shapeshifting, she made her skin burning to the touch, preventing Jenny from touching her, which she would have needed to do in order to shift Nyx away to the void of space as she might otherwise have done. She then spent her last few moments taunting Jenny with the idea that her self-serving nature (about to be demonstrated once again by her running away and living the planet's inhabitants to die) had been key in the loss of Michael. (COMIC: The Jenny Everywhere Chronicles)