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In Reality Z-25 31-H, Cleopatra was the last independent ruler of Egypt descended from Alexander the Great's general Ptolemy. When her rule over Egypt was threatened by Augustus, rather than let him claim the Philosopher's Stone over which she and her ancestors had been watching for generations, she had her handmaid take it down the Nile to safety. (COMIC: Nula! Naked and Alone!)
Behind the scenes
Historically, Octavian had yet to take on the name of “Augustus” by the death of Cleopatra.